4-Fluoro-2-methylaniline → HCID 69954748, compound

Participants

Reaction Steps

After 2-methyl-4-fluoroaniline(1.1 ml, 9.9 mmol) was added to a mixture solution of (S)-5,6-dimethyl-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(1.4 g, 4.8 mmol) obtained in the above Step 1 and dimethylformamide (10 ml), 0.90 g of the title compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence