HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoroaniline → 178307-44-3
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | HCID 54298115 | HCID 54298115 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 178307-44-3 | HCID 44535615 | 78.3% |
Reaction Steps
After 4-fluoroaniline(1 ml, 10 mmol) was added to a mixture solution of (S)-5,6-dimethyl-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(1.4 g, 4.8 mmol) and dimethylformamide(10 ml), 1.50 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750531 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-636e3f6ad6344b2baf2133e1f26d7921 |
| Source note | uspto-grants-1998_05 |