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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289515Generated: November 1, 2026

4-Fluoroaniline → 178307-44-3

https://huagongshe.com/reaction/1289515

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluoroanilineHCID 9731—
ReactantHCID 54298115HCID 54298115—
SolventDimethylformamideHCID 6228—
Product178307-44-3HCID 4453561578.3%

Reaction Steps

After 4-fluoroaniline(1 ml, 10 mmol) was added to a mixture solution of (S)-5,6-dimethyl-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(1.4 g, 4.8 mmol) and dimethylformamide(10 ml), 1.50 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-636e3f6ad6344b2baf2133e1f26d7921
Source noteuspto-grants-1998_05