HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluidine → HCID 18921801, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 5,6-Dimethyl-2-chloro4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine | HCID 11185318 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18921801 | HCID 18921801 | 27.3% |
Reaction Steps
After p-toluidine(0.45 g, 4.20 mmol) was added to a mixture solution of 5,6-dimethyl-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(0.80 g, 2.78 mmol) and dimethylformamide(5 ml), 0.30 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750531 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-a860fee56e4b4a7c8d2978ace2e06ae3 |
| Source note | uspto-grants-1998_05 |