HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,3,4-Tetrahydroisoquinoline → HCID 18921782, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,3,4-Tetrahydroisoquinoline | HCID 7046 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,4-Dichloro-6-methylpyrimidine | HCID 79471 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18921782 | HCID 18921782 | 59.7% |
Reaction Steps
In accordance with the same procedure as in Step 1 of Example 1, except that 6-methyl-2,4-dichloropyrimidine (3.26 g, 20 mmol), 1,2,3,4-tetrahydroisoquinoline(2.6 ml, 20.5 mmol), triethylamine(3.4 ml, 24.4 mmol) and N,N-dimethyl formamide (10 ml) were used as starting materials, 3.1 g of the titled compound was prepared. (Yield: 59.7%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750531 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-2deaec62d3cb40b68a5c36dec11e1486 |
| Source note | uspto-grants-1998_05 |