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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289538Generated: October 30, 2026

4-Fluoro-2-methylaniline → HCID 18921722, compound

https://huagongshe.com/reaction/1289538

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921782HCID 18921782—
SolventDimethylformamideHCID 6228—
ProductHCID 18921722HCID 1892172258.1%

Reaction Steps

After 2-methyl-4-fluoroaniline(0.8 ml, 7.2 mmol) was added to a mixture solution of 6-methyl-4-(1,2,3,4-tetrahydroisoquinoline-2-yl)-2-chloropyrimidine(1.0 g, 3.8 mmol) and dimethylformamide(10 ml), 0.85 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-cb68403464f04f76ab1b45f6ed72306c
Source noteuspto-grants-1998_05