HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-methylaniline → HCID 18921688, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-methylaniline | HCID 67982 | — |
| Reactant | 2-Chloro-5,6-dimethyl-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine | HCID 18315743 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18921688 | HCID 18921688 | 44% |
Reaction Steps
After 4-fluoro-2-methylaniline(0.8 ml, 7 mmol) was added to a mixture solution of 5,6-dimethyl-4-(1,2,3,4-tetrahydroisoquinoline-2-yl)-2-chloropyrimidine(1.0 g, 3.6 mmol) and dimethylformamide(10 ml), 0.58 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750531 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-30635b55fe3b4612b8864467ffc3ab54 |
| Source note | uspto-grants-1998_05 |