HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoroaniline → HCID 18921710, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | 2-Chloro-5,6-dimethyl-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine | HCID 18315743 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18921710 | HCID 18921710 | 48.4% |
Reaction Steps
After 4-fluoroaniline(0.7 ml, 7.4 mmol) was added to a mixture solution of 5,6-dimethyl-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(1.0 g, 3.6 mmol) and dimethylformamide(5 ml), 0.67 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750531 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-b308fec2b6a24b4b8d90dde117f39fb4 |
| Source note | uspto-grants-1998_05 |