Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289551Generated: November 2, 2026

4-Fluoro-2-methylaniline → HCID 18921718, compound

https://huagongshe.com/reaction/1289551

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921790HCID 18921790—
SolventDimethylformamideHCID 6228—
ProductHCID 18921718HCID 1892171853.5%

Reaction Steps

After 4-fluoro-2-methylaniline(0.5 ml, 3.6 mmol) was added to a mixture solution of 5-methyl-6-ethyl-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(0.7 g, 2.4 mmol) and dimethylformamide(5 ml), 0.53 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-06a1d12484a142c7b9af85fe8e3aa7e8
Source noteuspto-grants-1998_05