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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289556Generated: October 30, 2026

4-Fluoro-2-methylaniline → HCID 18921717, compound

https://huagongshe.com/reaction/1289556

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921761HCID 18921761—
SolventDimethylformamideHCID 6228—
ProductHCID 18921717HCID 1892171728.2%

Reaction Steps

After 4-fluoro-2-methylaniline(0.75 ml, 6.6 mmol) was added to a mixture solution of 4-(1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloro-5,6,7,8-tetrahydroquinazoline(0.90 g, 3.0 mmol) and dimethylformamide(5 ml), 0.36 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-bd9eece3683b44cca28ddbab1de4d413
Source noteuspto-grants-1998_05