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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289559Generated: October 31, 2026

O-Toluidine → HCID 18921726, compound

https://huagongshe.com/reaction/1289559

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantHCID 18921761HCID 18921761—
SolventDimethylformamideHCID 6228—
ProductHCID 18921726HCID 1892172649.1%

Reaction Steps

After 2-methylaniline(0.30 ml, 2.7 mmol) was added to a mixture solution of 4-(1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloro-5,6,7,8-tetrahydroquinazoline(0.75 g, 2.5 mmol) and dimethylformamide(5 ml), 0.50 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-2af4dcc9b7b1442eb67dfbeb00170d1d
Source noteuspto-grants-1998_05