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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289572Generated: November 3, 2026

4-Fluoroaniline → HCID 18921745, compound

https://huagongshe.com/reaction/1289572

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluoroanilineHCID 9731—
ReactantHCID 18921675HCID 18921675—
SolventDimethylformamideHCID 6228—
ProductHCID 18921745HCID 1892174552%

Reaction Steps

After 4-fluoroaniline(0.8 ml, 8.4 mmol) was added to a mixture solution of 6-methyl-2-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chloropyrimidine(1.5 g, 5.5 mmol) and dimethylformamide(10 ml), 1.1 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-0f4c9f4bf874419aa2a9824809e63302
Source noteuspto-grants-1998_05