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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289577Generated: October 30, 2026

4-Fluoro-2-methylaniline → HCID 18921698, compound

https://huagongshe.com/reaction/1289577

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921747HCID 18921747—
SolventDimethylformamideHCID 6228—
ProductHCID 18921698HCID 1892169838.1%

Reaction Steps

After 2-methyl-4-fluoroaniline(1.1 ml, 10.2 mmol) was added to a mixture solution of 6-ethyl-2-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chloropyrimidine(2.0 g, 7.0 mmol) and dimethylformamide(10 ml), 1.1 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-9fb19719a271434eba0e5415a0694f02
Source noteuspto-grants-1998_05