HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-methylaniline → HCID 18921705, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-methylaniline | HCID 67982 | — |
| Reactant | HCID 18921673 | HCID 18921673 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18921705 | HCID 18921705 | 72.7% |
Reaction Steps
After 2-methyl-4-fluoroaniline(0.7 ml, 6.3 mmol) was added to a mixture solution of 5,6-dimethyl-2-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chloropyrimidine(0.85 g, 3.0 mmol) and dimethylformamide(10 ml), 0.9 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750531 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-c9c4142d661b4d54af7c33ac2b2cbd15 |
| Source note | uspto-grants-1998_05 |