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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289581Generated: October 31, 2026

4-Fluoro-2-methylaniline → HCID 18921705, compound

https://huagongshe.com/reaction/1289581

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921673HCID 18921673—
SolventDimethylformamideHCID 6228—
ProductHCID 18921705HCID 1892170572.7%

Reaction Steps

After 2-methyl-4-fluoroaniline(0.7 ml, 6.3 mmol) was added to a mixture solution of 5,6-dimethyl-2-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chloropyrimidine(0.85 g, 3.0 mmol) and dimethylformamide(10 ml), 0.9 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-c9c4142d661b4d54af7c33ac2b2cbd15
Source noteuspto-grants-1998_05