4-Fluoroaniline → HCID 69956482, compound

Participants

Reaction Steps

After 4-fluoroaniline(0.6 ml, 6.3 mmol) was added to mixture solution of (S)-5,6-dimethyl-2-(1-methyl-1,2,3,4-tetrahydroisoquinoline-2-yl)-4-chloropyrimidine(0.85 g, 3.0 mmol) prepared in Step 2 of Example 62 and dimethylformamide (10 ml), 0.55 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.

Provenance & Evidence