HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylaniline → HCID 67626540, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylaniline | HCID 7515 | — |
| Reactant | HCID 54324573 | HCID 54324573 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67626540 | HCID 67626540 | 44.4% |
Reaction Steps
After N-methylaniline(0.6 ml, 5 mmol) was added to a mixture solution of (S)-5,6-dimethyl-2-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chloropyrimidine(0.7 g, 2.4 mmol) prepared in the Step 2 of Example 62 and dimethylformamide(10 ml), 0.42 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750531 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-10e80252c5484f3d8295216cb2f31361 |
| Source note | uspto-grants-1998_05 |