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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289588Generated: October 31, 2026

N-Methylaniline → HCID 67626540, compound

https://huagongshe.com/reaction/1289588

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylanilineHCID 7515—
ReactantHCID 54324573HCID 54324573—
SolventDimethylformamideHCID 6228—
ProductHCID 67626540HCID 6762654044.4%

Reaction Steps

After N-methylaniline(0.6 ml, 5 mmol) was added to a mixture solution of (S)-5,6-dimethyl-2-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chloropyrimidine(0.7 g, 2.4 mmol) prepared in the Step 2 of Example 62 and dimethylformamide(10 ml), 0.42 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-10e80252c5484f3d8295216cb2f31361
Source noteuspto-grants-1998_05