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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289590Generated: November 3, 2026

4-Fluoro-2-methylaniline → HCID 9801035, compound

https://huagongshe.com/reaction/1289590

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921658HCID 18921658—
SolventDimethylformamideHCID 6228—
ProductHCID 9801035HCID 980103530.1%

Reaction Steps

After 2-methyl-4-fluoroaniline(0.3 ml, 2.7 mmol) was added to a mixture solution of (5,6-dimethyl-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chloropyrimidine(0.30 g, 1.0 mmol) and dimethylformamide(10 ml), 0.12 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-f323507023b447d89d75fbc415b77cca
Source noteuspto-grants-1998_05