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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289599Generated: October 31, 2026

4-Fluoro-2-methylaniline → HCID 18921664, compound

https://huagongshe.com/reaction/1289599

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921695HCID 18921695—
SolventDimethylformamideHCID 6228—
ProductHCID 18921664HCID 1892166431.1%

Reaction Steps

After 4-fluoro-2-methylaniline(0.3 ml, 2.7 mmol) was added to a mixture solution of 2-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-4-chloro-5,6,7,8-tetrahydroquinazoline(0.35 g, 1.1 mmol) and dimethylformamide(5 ml), 0.15 g of the titled compound was obtained in accordance with the same procedure as in Step 4 of Example 57.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-486fee2305bf4b6b9bb1cc4e5d1c4c38
Source noteuspto-grants-1998_05