Methyl iodide → 3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

HRID 1289665Notes

Reaction equation

HRID 1289665 reaction equation
[Cl:1][C:2]1[C:6]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:5][S:4][N:3]=1.[CH3:13][I:14]>CC(C)=O>[I-:14].[Cl:1][C:2]1[C:6]([C:7]2[CH:8]=[N+:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:5][S:4][N:3]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 104881643-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole

Product 1

HCID 190753343-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodideYield 100.1%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of 3-(3-chloro-1,2,5-thiadiazol-4-yl)pyridine (1.98 g, 10 mmol) and methyl iodide (4.25 g, 30 mmol) in acetone (10 ml) was stirred at room temperature for 16 h. The precipitate was collected by filtration to yield 3.40 g (100%) of the title compound.

Workup

  1. filtrationThe precipitate was collected by filtration

Sources & evidence

ORD record
ord-c37e6fd3e5f8470a9303185f8c263355
Source dataset
uspto-grants-1998_05
Patent number
US05750541

Reaction notes

Loading…