反应详情

The synthesis method of Example 1-(1) was applied. The compound (18.3 g) obtained in (2) above, methylisothiourea sulfate (81.6 g), sodium hydroxide (11.7 g), water (90 ml) and methanol (180 ml) were used as reagents and the mixture was reacted at 60° C. for 48 hours to give 39.7 g of a yellow solid. A portion (21.2 g) from the obtained solid was used in the next reaction.

1. customthe mixture was reacted at 60° C. for 48 hours