Benzaldehyde → 5-Amino-3-[(N-benzylidene)amino]-1-[methylamino(thiocarbonyl)]-1H-1,2,4-triazole

Participants

Reaction Conditions

Reaction Steps

The compound (3.00 g) obtained in Example 31, ethanol (100 ml), benzaldehyde (1.99 g) and DL-camphor-10-sulfonic acid (110 mg) were stirred with heating in an oil bath at 60° C. for 5 hours. After the reaction, the mixture was cooled to room temperature and the resulting crystals were collected by filtration, which were washed with ethanol and dried to give 2.13 g of pale-yellow crystals (yield 47%).

Provenance & Evidence