Dimethylformamide → HCID 18922232, compound

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Reaction Steps

The synthesis method of Example 1-(3) was applied. The compound (3.86 g) obtained in (2) above, dimethylformamide (50 ml) and methyl isothiocyanate (1.81 g) were used as reagents and the mixture was stirred at room temperature for 6 days. After the reaction, silica gel column chromatography (chloroform-methanol) and recrystallization from chloroform gave 961 mg of white crystals (yield 18%).

Provenance & Evidence