HCID 18922022, compound → HCID 18922078, compound

HRID 1289816Notes

Reaction equation

HRID 1289816 reaction equation
[CH3:1][C:2](C)=[CH:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:26])[C:14]([CH:21]2[CH2:25][CH2:24][CH2:23][CH2:22]2)([OH:20])[C:15]2[S:19][CH:18]=[N:17][CH:16]=2)[CH2:8][CH2:7]1.Cl.Cl.N[CH:31]1[CH2:36]CN(CC2CCCCCC2)C[CH2:32]1>>[CH:4]1([CH2:5][N:6]2[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:26])[C:14]([CH:21]3[CH2:22][CH2:23][CH2:24][CH2:25]3)([OH:20])[C:15]3[S:19][CH:18]=[N:17][CH:16]=3)[CH2:8][CH2:7]2)[CH2:3][CH2:2][CH2:1][CH2:36][CH2:31][CH2:32]1

Participants

3

Reactant 2

HCID 18922022HCID 18922022, compoundHCID 18922028HCID 18922028, compound

Product 1

HCID 18922078HCID 18922078, compound

Procedure

The title compound was prepared in the same manner as described in Step 4 of Example 22 using 2-cyclopentyl-2-hydroxy-2-(5-thiazolyl)acetic acid obtained in Example 57 and 4-amino-1-(cycloheptylmethyl)piperidine dihydrochloride.

Sources & evidence

ORD record
ord-c2709a2ef2344e738621da30b903d03d
Source dataset
uspto-grants-1998_05
Patent number
US05750540

Reaction notes

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