HCID 18922028, compound → HCID 18922118, compound

HRID 1289817Notes

Reaction equation

HRID 1289817 reaction equation
[CH3:1][C:2](C)=[CH:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:26])[C:14]([CH:21]2[CH2:25][CH2:24][CH2:23][CH2:22]2)([C:16]2[O:17][CH:18]=[CH:19][CH:20]=2)[OH:15])[CH2:8][CH2:7]1.Cl.Cl.N[CH:31]1[CH2:36]CN(CC2CCCCCC2)C[CH2:32]1>>[CH:4]1([CH2:5][N:6]2[CH2:7][CH2:8][CH:9]([NH:12][C:13](=[O:26])[C:14]([C:16]3[O:17][CH:18]=[CH:19][CH:20]=3)([CH:21]3[CH2:22][CH2:23][CH2:24][CH2:25]3)[OH:15])[CH2:10][CH2:11]2)[CH2:36][CH2:31][CH2:32][CH2:1][CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 18922028HCID 18922028, compoundHCID 18922121HCID 18922121, compound

Product 1

HCID 18922118HCID 18922118, compound

Procedure

The title compound was prepared in the same manner as described in Step 4 of Example 22 using 2-cyclopentyl-2-(2-furyl)-2-hydroxyacetic acid obtained in Example 50 and 4-amino-1-(cycloheptylmethyl)piperidine dihydrochloride.

Sources & evidence

ORD record
ord-b2fe6c7d89ed476589b3a9dc8ccccf57
Source dataset
uspto-grants-1998_05
Patent number
US05750540

Reaction notes

Loading…