HCID 18922028, compound → HCID 18922052, compound

HRID 1289818Notes

Reaction equation

HRID 1289818 reaction equation
CC(C)=CCC[N:6]1[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:26])[C:14]([CH:21]2[CH2:25][CH2:24][CH2:23][CH2:22]2)([OH:20])[C:15]2[S:16][CH:17]=[CH:18][N:19]=2)[CH2:8][CH2:7]1.Cl.Cl.NC1CCN([CH2:37][CH:38]2[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40][CH2:39]2)CC1>>[CH:38]1([CH2:37][N:6]2[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:26])[C:14]([CH:21]3[CH2:25][CH2:24][CH2:23][CH2:22]3)([OH:20])[C:15]3[S:16][CH:17]=[CH:18][N:19]=3)[CH2:8][CH2:7]2)[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40][CH2:39]1

Participants

3

Reactant 2

HCID 18922028HCID 18922028, compoundHCID 18922053HCID 18922053, compound

Product 1

HCID 18922052HCID 18922052, compound

Procedure

The title compound was prepared in the same manner as described in Step 4 of Example 22 using 2-cyclopentyl-2-hydroxyl-2-(2-thiazolyl)acetic acid obtained in Example 51 and 4-amino-1-(cycloheptylmethyl)piperidine dihydrochloride.

Sources & evidence

ORD record
ord-dd9283b0f9334074bca3554ae1119295
Source dataset
uspto-grants-1998_05
Patent number
US05750540

Reaction notes

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