HCID 18922028, compound → HCID 18922066, compound

HRID 1289819Notes

Reaction equation

HRID 1289819 reaction equation
[CH3:1][C:2](C)=[CH:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:27])[C:14]([CH:22]2[CH2:26][CH2:25][CH2:24][CH2:23]2)([OH:21])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)[CH2:8][CH2:7]1.Cl.Cl.N[CH:32]1[CH2:37]CN(CC2CCCCCC2)C[CH2:33]1>>[CH:4]1([CH2:5][N:6]2[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:27])[C:14]([CH:22]3[CH2:23][CH2:24][CH2:25][CH2:26]3)([OH:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=3)[CH2:8][CH2:7]2)[CH2:37][CH2:32][CH2:33][CH2:1][CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 18922028HCID 18922028, compoundHCID 18922036HCID 18922036, compound

Product 1

HCID 18922066HCID 18922066, compound

Procedure

The title compound was prepared in the same manner as described in Sept 4 of Example 22 using 2-cyclopentyl-2-hydroxy-2-(2-pyridyl)acetic acid obtained in Example 52 and 4-amino-1-(cycloheptylmethyl)piperidine dihydrochloride.

Sources & evidence

ORD record
ord-288b16db4ffe4034846de95977cd8381
Source dataset
uspto-grants-1998_05
Patent number
US05750540

Reaction notes

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