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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 128982Generated: October 29, 2026

Hydrochloric Acid → HCID 70197051, compound

https://huagongshe.com/reaction/128982

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 54060679HCID 54060679—
ReactantHCID 70193605HCID 70193605—
ReactantHCID 70195376HCID 70195376—
ProductHCID 70197051HCID 70197051—

Reaction Steps

By steps analogous to steps (a) to (c) of Synthetic Example 14, the product from step (a) was converted to (R)-3-(1-methyl -1,2,3,6-tetrahydro-4-pyridyl)-5-(2-oxo-1,3-oxazolidin-4-ylmethyl) -1H-indole hydrate, mp 229°-231° C., [α]D18 +24.9° (c=0.5, IN aqu. HCl). Elemental analysis and 1H NMR were consistent with the proposed structure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05466699
Source datasetuspto-grants-1995_11
ORD IDord-722bc40db5d4489182d916a7b7727dd8
Source noteuspto-grants-1995_11