HCID 18922028, compound → HCID 18922104, compound

HRID 1289820Notes

Reaction equation

HRID 1289820 reaction equation
[CH3:1][C:2](C)=[CH:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:28])[C:14]([CH:23]2[CH2:27][CH2:26][CH2:25][CH2:24]2)([C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[CH:17]=2)[OH:15])[CH2:8][CH2:7]1.Cl.Cl.N[CH:33]1[CH2:38]CN(CC2CCCCCC2)C[CH2:34]1>>[CH:4]1([CH2:5][N:6]2[CH2:7][CH2:8][CH:9]([NH:12][C:13](=[O:28])[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[CH:17]=3)([CH:23]3[CH2:27][CH2:26][CH2:25][CH2:24]3)[OH:15])[CH2:10][CH2:11]2)[CH2:38][CH2:33][CH2:34][CH2:1][CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 18922028HCID 18922028, compoundHCID 18922045HCID 18922045, compound

Product 1

HCID 18922104HCID 18922104, compound

Procedure

The title compound was prepared in the same manner as described in Step 4 of Example 22 using 2-(3-fluorophenyl)-2-cyclopentyl-2-hydroxyacetic acid obtained in Example 53 and 4-amino-1-(cycloheptylmethyl)piperidine dihydrochloride.

Sources & evidence

ORD record
ord-97b2ecae46044bdaa3080c6bbbacd7d1
Source dataset
uspto-grants-1998_05
Patent number
US05750540

Reaction notes

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