HCID 18922028, compound → HCID 18922096, compound

HRID 1289821Notes

Reaction equation

HRID 1289821 reaction equation
C[C:2]([CH3:29])=[CH:3][CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][CH:9]([NH:12][C:13](=[O:28])[C:14]([CH:23]2[CH2:27][CH2:26][CH2:25][CH2:24]2)([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[F:22])[OH:15])[CH2:8][CH2:7]1.Cl.Cl.N[CH:33]1[CH2:38]CN(CC2CCCCCC2)C[CH2:34]1>>[CH:4]1([CH2:5][N:6]2[CH2:7][CH2:8][CH:9]([NH:12][C:13](=[O:28])[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[F:22])([CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27]3)[OH:15])[CH2:10][CH2:11]2)[CH2:38][CH2:33][CH2:34][CH2:29][CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 18922028HCID 18922028, compoundHCID 18922086HCID 18922086, compound

Product 1

HCID 18922096HCID 18922096, compound

Procedure

The title compound was prepared in the same manner as described in Step 4 of Example 22 using 2-(2-fluorophenyl)-2-cyclopentyl-2-hydroxyacetic acid obtained in Example 54 and 4-amino-1-(cycloheptylmethyl)piperidine dihydrochloride.

Sources & evidence

ORD record
ord-02b5fd54490f437e977ffd1acbdcbf06
Source dataset
uspto-grants-1998_05
Patent number
US05750540

Reaction notes

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