HCID 18922028, compound → HCID 18922064, compound

HRID 1289822Notes

Reaction equation

HRID 1289822 reaction equation
C(O)(=O)/C=C/C(O)=O.CC(C)=CCC[N:14]1[CH2:19][CH2:18][CH:17]([NH:20][C:21](=[O:36])[C:22]([CH:31]2[CH2:35][CH2:34][CH2:33][CH2:32]2)([C:24]2[CH:29]=[CH:28][C:27]([F:30])=[CH:26][CH:25]=2)[OH:23])[CH2:16][CH2:15]1.Cl.Cl.NC1CCN([CH2:47][CH:48]2[CH2:54][CH2:53][CH2:52][CH2:51][CH2:50][CH2:49]2)CC1>>[CH:48]1([CH2:47][N:14]2[CH2:19][CH2:18][CH:17]([NH:20][C:21](=[O:36])[C:22]([CH:31]3[CH2:35][CH2:34][CH2:33][CH2:32]3)([C:24]3[CH:25]=[CH:26][C:27]([F:30])=[CH:28][CH:29]=3)[OH:23])[CH2:16][CH2:15]2)[CH2:54][CH2:53][CH2:52][CH2:51][CH2:50][CH2:49]1

Participants

3

Reactant 2

HCID 18922028HCID 18922028, compoundHCID 18922099HCID 18922099, compound

Product 1

HCID 18922064HCID 18922064, compound

Procedure

The title compound was prepared in the same manner as described in Step 4 of Example 22 using 2-cyclopentyl-2-(4-fluorophenyl)-2-hydroxyacetic acid obtained in Example 55 and 4-amino-1-(cycloheptylmethyl)piperidine dihydrochloride.

Sources & evidence

ORD record
ord-2f8675e4c6074d5489c99e03dc418db6
Source dataset
uspto-grants-1998_05
Patent number
US05750540

Reaction notes

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