Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzyl Alcohol | HCID 244 | — |
| Reactant | epsilon-CAPROLACTONE | HCID 10401 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Product | Benzyl 6-hydroxyhexanoate | HCID 15224618 | 26% |
Reaction Steps
A mixture of 6-hexanolactone (40 g, 0.35 mol), phenylmethanol (70 g, 0.647 mol), and conc. sulfuric acid (40 drops) was heated at 50° C. overnight. The resulting mixture was purified by column chromatography (hexane, 5-30% ethyl acetate/hexane) and distilled to afford 20.1 g (26%) of 6-hydroxyhexanoic acid phenylmethyl ester, b.p. 70°-75° C./1 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05750550 |
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| Source dataset | uspto-grants-1998_05 |
|---|
| ORD ID | ord-88b4421ed80245eca151443e737e1075 |
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| Source note | uspto-grants-1998_05 |
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