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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289953Generated: October 30, 2026

Iodoacetamide → 1-(S)-(1-(R)-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(S)-phenyl-3-(R)-(aminocarbonylmethylamino)cyclopentane

https://huagongshe.com/reaction/1289953

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoacetamideHCID 3727—
Reactant1-(s)-(1-(r)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-2-(s)-phenyl-3-(r)-aminocyclopentaneHCID 22885635—
Product1-(S)-(1-(R)-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(S)-phenyl-3-(R)-(aminocarbonylmethylamino)cyclopentaneHCID 54282460—

Reaction Steps

The title compound was prepared using the amine from Example 28 and iodoacetamide using essentially the same procedure as Example 10. Mass spec (NH3 /CI): 475 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750549
Source datasetuspto-grants-1998_05
ORD IDord-c29c40f56c474384ab7ebd996ddf7c20
Source noteuspto-grants-1998_05