Pyrrolidine → HCID 22885752, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 500 mg of product from Step C in 3.0 mL of acetonitrile was added 0.40 mL of pyrrolidine. The reaction was heated at 90° C. for 3 days in a sealed vial and then concentrated. The residue was purified by flash chromatography eluting with 0 to 5% methanol in methylene chloride to obtain 483 mg of title compound. Mass spec (NH3 /CI): 517 (M+1).

Provenance & Evidence