HCID 10726780, compound → HCID 67667608, compound

HRID 1289982Notes

Reaction equation

HRID 1289982 reaction equation
[CH3:1][O:2][C:3]([CH:5]1[CH2:9][CH2:8][CH:7]([N:10]=[N+]=[N-])[CH:6]1[C:13]1[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=1)=[O:4].[O:20]1[CH:24]=[CH:23][CH:22]=[C:21]1[C:25]1[CH:26]=[CH:27][C:28]([O:33][CH3:34])=[C:29]([CH:32]=1)[CH:30]=O>>[CH3:1][O:2][C:3]([CH:5]1[CH2:9][CH2:8][CH:7]([NH:10][CH2:30][C:29]2[CH:32]=[C:25]([C:21]3[O:20][CH:24]=[CH:23][CH:22]=3)[CH:26]=[CH:27][C:28]=2[O:33][CH3:34])[CH:6]1[C:13]1[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=1)=[O:4]

Participants

3

Reactant 2

HCID 10726780HCID 10726780, compoundHCID 18922366HCID 18922366, compound

Product 1

HCID 67667608HCID 67667608, compound

Procedure

The title compound was prepared by employing the method described in Example 91, Step D with (1RS,2RS,3RS)-2-(4-fluorophenyl)-3-azidocyclopentanecarboxylic acid methyl ester (from Example 89, Step A) and the known 5-(furan-2-yl)-2-methoxybenzaldehyde (P. J. Ward, et al., J. Med. Chem. 1995, 38, 4985-92).

Sources & evidence

ORD record
ord-335fe8bf3fbb40fa8bca3a13e2a7594a
Source dataset
uspto-grants-1998_05
Patent number
US05750549

Reaction notes

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