HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromopyridine → 2-Methoxy-5-(pyridin-3-yl)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | (3-Formyl-4-methoxyphenyl)boronic acid | HCID 2759225 | — |
| Product | 2-Methoxy-5-(pyridin-3-yl)benzaldehyde | HCID 22620077 | — |
Reaction Steps
The title compound was prepared by employing the method described in Example 111, Step A with (3-formyl-4-methoxyphenyl)-boronic acid and the commercially available 3-bromopyridine. NMR (400 MHz, CDCl3): δ 10.53 (s, 1H), 8.89 (d, 1H, J=2 Hz), 8.63 (dd, 1H, J=5,1 Hz), 8.10 (dt, 1H, J=8,2 Hz), 8.09 (d, 1H, J=2 Hz), 7.83 (dd, 1H, J=9,2 Hz), 7.56 (dd, 1H, J=8,5 Hz), 7.17 (d, 1H, J=9 Hz), 4.02 (s, 3H). Mass spectrum (NH3 /CI): 214 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750549 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-d87f0ed4e36646948f21e211327c1661 |
| Source note | uspto-grants-1998_05 |