HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 5-(2-chloroacetyl)-8-phenylmethoxy-1H-quinolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 5-Acetyl-8-(benzyloxy)-1,2-dihydroquinolin-2-one | HCID 13375444 | — |
| Reactant | Trimethylbenzylammonium Dichloroiodate | HCID 56924451 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 5-(2-chloroacetyl)-8-phenylmethoxy-1H-quinolin-2-one | HCID 10903550 | — |
Reaction Steps
A solution of 5-acetyl-8-benzyloxycarbostyril (1.75 g, 6 mMol) in 1,2-dichloroethane (60 ml)/methanol (40 ml) and benzyltrimethylammonium dichloroiodate (4.2 g, 12 mMol) was heated at 60° C. under an argon atmosphere for 2 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750701 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-3f7e72c4f833481d833c6b7225556d74 |
| Source note | uspto-grants-1998_05 |