HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinic anhydride → HCID 54095300, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinic anhydride | HCID 7922 | — |
| Reactant | HCID 54562188 | HCID 54562188 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 54095300 | HCID 54095300 | 100.4% |
Reaction Steps
A solution of 8-[3-[N-(4-aminocinnamoylglycyl)-N-methylamino]-2,6-dichlorobenzyloxy]-3-bromo-2-methylimidazo[1,2-a]pyridine (150 mg) and succinic anhydride (26 mg) in dioxane (3 ml) was refluxed for 2 hours. After cooling, the solution was removed in vacuo to give 3-bromo-8-[3-[N-[4-(3-carboxypropionamido)cinnamoylglycyl]-N-methylamino]-2,6-dichlorobenzyloxy]-2-methylimidazo[1,2-a]pyridine (175 mg) as amorphous.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750699 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-f8ecaba88ca649e9a1fde9b7c180bc31 |
| Source note | uspto-grants-1998_05 |