反应详情

Ethyl 2-hydroxy-2-(6-methoxynaphth-2-yl)propionate (5,0 g, 18,2 mmol), Dowex HCR-W2 strong acid exchange resin (0,50 g) and acetic anhydride (4,09 g, 40,1 mmol) were added to acetic acid (100 g) and refluxed for 7 hours, cooled and the resin was removed by filtration. Ethyl 2-(6-methoxynaphth-2-yl)acrylate was produced in 64,6% yield and could be used without purification.

1. temperaturerefluxed for 7 hours
2. temperaturecooled
3. customthe resin was removed by filtration