HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-Methoxynaphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 10858682 | HCID 10858682 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-Methoxynaphthalene | HCID 7119 | — |
| Product | Ethyl 2-(6-methoxynaphthalen-2-yl)propanoate | HCID 2732945 | — |
Reaction Steps
Ethyl 2-hydroxy-2-(6-methoxynaphth-2-yl)propionate (7,5 g, 27,3 mmol), acetic anhydride (6,14 g, 60,2 mmol), toluene (37 ml) and palladium catalyst (5% on carbon, 0,75 g) were heated (140° C.) under a hydrogen atmosphere (10 bar) for 14 hours. Ethyl 2-(6-methoxynaphth-2-yl)propionate was formed with a selectivity of 92% at a 2-methoxynaphthalene conversion of 60%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750764 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-e8016fd9bd834cd99440a28d1e80058b |
| Source note | uspto-grants-1998_05 |