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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1290434Generated: October 25, 2026

Triethylamine → (S)-2-[[[(4-Nitrophenyl)methoxy]carbonyl]amino]butanoic Acid

https://huagongshe.com/reaction/1290434

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant(-)-2-Aminobutyric acidHCID 80283—
ReactantCarbonic acid 4-Nitrophenyl (4-Nitrophenyl)methyl EsterHCID 21829967—
SolventWater ethanolHCID 19096565—
Product(S)-2-[[[(4-Nitrophenyl)methoxy]carbonyl]amino]butanoic AcidHCID 5366793881.5%

Reaction Steps

The title compound is prepared by the procedure of Example 255 using 29.46 g of product from Example 254, 9.5 g of L-2-aminobutyric acid, 25.5 ml of triethylamine and 1112 ml of 4:1 ethyl alcohol/water to give 21.2 g of the desired product after chromatography.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750735
Source datasetuspto-grants-1998_05
ORD IDord-e53f94e9969c44999da4e7b11ef0ed38
Source noteuspto-grants-1998_05