HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 2-Chloromethyl-4-isopropyl-6-hydroxysaccharin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 4-Isopropyl-6-hydroxy-2-phenylthiomethylsaccharin | HCID 10316654 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Chloromethyl-4-isopropyl-6-hydroxysaccharin | HCID 10266200 | — |
Reaction Steps
4-isopropyl-6-hydroxy-2-phenylthiomethylsaccharin (1.78 g) in methylene chloride was treated with sulfuryl chloride (0.43 mL, 0.73 g) to afford 1.2 g 84%) of 2-chloromethyl-4-isopropyl-6-hydroxysaccharin, m.p. 149°-150° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05466701 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-5aee0282e98242f8b42122bfe57ee5a4 |
| Source note | uspto-grants-1995_11 |