Ethyl 3-benzyl-4-[4-[4-(4-pyridyl)piperazin-1-yl]phenoxy]butyrate → 3-Benzyl-4-[4-[4-(4-pyridyl)piperazin-1-yl]phenoxy]-butyric acid

Participants

Reaction Steps

In a similar manner to Example 50 ,but starting from the product of step i) was prepared RS ethyl 3-benzyl-4-[4-[4-(4-pyridyl)piperazin-1-yl]phenoxy]butyrate in 40% yield as an oil; NMR (CDCl3) δ 8.34(2H,d), 7.29(5H,m), 6.9(4H,m), 6.72(2H,m), 5.13(2H,q), 3.85(2H,m), 3.5(4H,m), 3.3(4H,m), 2.9-2.38(5H,m), 1.26(3H,t); m/e 460(M+H)+.

Provenance & Evidence