Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 825293 | HCID 825293 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 7-Ethyl-3-methyl-1H-indol-6-amine | HCID 21218287 | — |
Reaction Steps
A mixture of 0.5 l of 96° ethanol, 0.5 l of glacial acetic acid and 100 g of hydrogen-reduced pure iron is heated to 90° C. 51 g of 3-methyl-6-nitro-7-ethylindole are added in portions over 15 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05752982 |
|---|
| Source dataset | uspto-grants-1998_05 |
|---|
| ORD ID | ord-26b3eadcf140474993e9b1c9c1144a2d |
|---|
| Source note | uspto-grants-1998_05 |
|---|
