HCID 21218301, compound → HCID 21218297, compound

HRID 1290568Notes

Reaction equation

HRID 1290568 reaction equation
[N+:1]([C:4]1[C:12]([CH2:13][CH3:14])=[C:11]2[C:7]([CH2:8][CH2:9][NH:10]2)=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[C:12]([CH2:13][CH3:14])=[C:11]2[C:7]([CH:8]=[CH:9][NH:10]2)=[CH:6][CH:5]=1

Participants

4

Reactant 1

HCID 21218301HCID 21218301, compound

Product 1

HCID 21218297HCID 21218297, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

38.4 g of 6-nitro 7-ethylindoline were dissolved in 120 ml of absolute ethanol to which were added 19.2 g of palladium on charcoal at 10% (moisture 50%) and then heated to reflux for 2 hours.

Workup

  1. temperatureheated
  2. temperatureto reflux for 2 hours

Sources & evidence

ORD record
ord-6d5e87844fa744baac018f593978ae36
Source dataset
uspto-grants-1998_05
Patent number
US05752982

Reaction notes

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