2-Piperidone → 1-(Furan-3-carbonyl)piperidin-2-one

HRID 1290578Notes

Reaction equation

[O:1]1[CH:5]=[CH:4][C:3]([C:6]([N:8]2[CH2:14][CH2:13][CH2:12][CH2:11]C[C:9]2=[O:15])=[O:7])=[CH:2]1.C1(=O)NCCCC1>>[O:1]1[CH:5]=[CH:4][C:3]([C:6]([N:8]2[CH2:14][CH2:13][CH2:12][CH2:11][C:9]2=[O:15])=[O:7])=[CH:2]1

Participants

Reactant 2

HCID 126652-Piperidone

HCID 18916104HCID 18916104, compound

Product 1

HCID 189160871-(Furan-3-carbonyl)piperidin-2-one

Procedure

Synthesized as for N-(3-furoyl)caprolactam (Example XI) using valerolactam (Aldrich) in place of caprolactam.

Sources & evidence

ORD record: ord-969c339bde0f47caa93428ae9e2d25bc
Source dataset: uspto-grants-1998_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05753138

Reaction notes

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