Nitric Acid → HCID 18916400, compound

HRID 1290633Notes

Reaction equation

HRID 1290633 reaction equation
[Cl:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([Cl:11])[CH:8]=[CH:7][C:5]=2[N:6]=1.S(=O)(=O)(O)O.[N+:17]([O-])([OH:19])=[O:18]>>[Cl:1][C:2]1[S:3][C:4]2[C:10]([N+:17]([O-:19])=[O:18])=[C:9]([Cl:11])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

4

Reactant 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 771762,6-Dichlorobenzothiazole

Product 1

HCID 18916400HCID 18916400, compound

Procedure

This compound was prepared in the manner of Step D, Example 6, with 8.0 grams (39 mmole) of 2,6-dichlorobenzothiazole, 45 mL of concentrated sulfuric acid, and 3.8 mL (60 mmole) of concentrated nitric acid as reagents. The material was purified by column chromatography on silica gel. Elution was accomplished with 3:1 heptane:ethyl acetate. The product-containing fractions were combined and concentrated under reduced pressure, yielding 2,6-dichloro-7 nitrobenzothiazole. The NMR spectrum was consistent with the proposed structure.

Workup

  1. customThe material was purified by column chromatography on silica gel
  2. washElution
  3. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-dd3565df9a6e41dc8178179d61f5d069
Source dataset
uspto-grants-1998_05
Patent number
US05753595

Reaction notes

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