HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-(2-nitrophenoxy)butanoate → Ethyl 4-(2-aminophenoxy)butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-(2-nitrophenoxy)butanoate | HCID 12433959 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Ethyl 4-(2-aminophenoxy)butanoate | HCID 11816929 | — |
Reaction Steps
A solution of (3) (1.27 g, 5.0 mM) in 15 mL ethyl acetate containing 200 mg of 57% palladium on carbon is reacted in a hydrogen atmosphere (40 psig.) at room temperature until hydrogen uptake ceases. The mixture is then filtered and concentrated in vacuo to yield 1.0+g of (4) as an oil/low melting solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05753641 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-9baa62f910444cf4b3689380998508bb |
| Source note | uspto-grants-1998_05 |