HCID 580518, compound → HCID 70110837, compound

HRID 1290727Notes

Reaction equation

HRID 1290727 reaction equation
[CH3:1][NH:2][C:3](SC)=[C:4]([C:10]#[N:11])[C:5]([O:7][CH2:8][CH3:9])=[O:6].[NH2:14][CH2:15][CH:16]1[O:21][CH2:20][CH2:19][N:18]([CH2:22][C:23]2[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=2)[CH2:17]1>>[F:29][C:26]1[CH:27]=[CH:28][C:23]([CH2:22][N:18]2[CH2:19][CH2:20][O:21][CH:16]([CH2:15][NH:14][C:3]([NH:2][CH3:1])=[C:4]([C:10]#[N:11])[C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH2:17]2)=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 580518HCID 580518, compoundHCID 102427352-Aminomethyl-4-(4-fluorobenzyl)morpholine

Product 1

HCID 70110837HCID 70110837, compoundYield 53%

Procedure

This compound was synthesized as a yellow oily substance from ethyl 3-methylamino-3-methylthio-2-cyanoacrylate and 2-aminomethyl-4-(p-fluorobenzyl)morpholine according to the same procedure as in Example 8. Yield=53%.

Sources & evidence

ORD record
ord-cef3bef002454f1fb0af8c3cab970d4a
Source dataset
uspto-grants-1998_05
Patent number
US05753654

Reaction notes

Loading…