Methyl Isocyanate → HCID 18918069, compound

HRID 1290730Notes

Reaction equation

HRID 1290730 reaction equation
[NH2:1][CH2:2][CH:3]1[O:8][CH2:7][CH2:6][N:5]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)[CH2:4]1.[CH3:17][N:18]=[C:19]=[O:20]>>[F:16][C:13]1[CH:14]=[CH:15][C:10]([CH2:9][N:5]2[CH2:6][CH2:7][O:8][CH:3]([CH2:2][NH:1][C:19]([NH:18][CH3:17])=[O:20])[CH2:4]2)=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 12228Methyl IsocyanateHCID 102427352-Aminomethyl-4-(4-fluorobenzyl)morpholine

Product 1

HCID 18918069HCID 18918069, compoundYield 65%

Procedure

This compound was synthesized from 2-aminomethyl-4-(p-fluorobenzyl)morpholine and methyl isocyanate according to the same procedure as in Example 21. Yield=65%.

Sources & evidence

ORD record
ord-23aa8db4e3a64a118cbd3472c70b26bb
Source dataset
uspto-grants-1998_05
Patent number
US05753654

Reaction notes

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