反应详情

The procedure is performed as in Example 17 for the preparation of 10-(2-furylmethylene)-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, but starting with 3 g of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, 60 ml of dimethyl sulphoxide, 0.96 g of sodium hydride and 1.6 g of 3-pyridinecarboxaldehyde. 1.38 g of 10-(3-pyridylmethylene)-5H,10H-imidazo[1,2-a]indeno-[1,2-e]pyrazin-4-one are obtained, in the form of a yellow-orange solid melting above 260° C. (Analysis % calculated C: 73.07, H: 3.87, N: 17.94, O: 5.12, % found C: 73.1, H: 3.9, N: 17.9, O: 5.1).