Dimethyl Sulfoxide → HCID 67015252, compound

Participants

Reaction Steps

The procedure is performed as in Example 28, but starting with 3 g of 5H,10H-imidazo[1,2-a]indeno-[1,2-e]pyrazin-4-one, 60 ml of dimethyl sulphoxide, 0.96 g of 80% sodium hydride and 3.18 g of 4-quinolincarboxaldehyde. After treating with water and acetic acid, the suspension obtained is filtered and the solid thus isolated is washed with 2×30 ml of water and then 4×30 ml of acetone and dried at 100° C. under vacuum (2 mmHg; 0.26 kPa). 3.9 g of 10-(4-quinolylmethylene)-5H,10H-imidazo[1,2-a]indeno-[1,2-e]pyrazin-4-one are obtained, in the form of an orange solid melting above 260° C. (Analysis % calculated C: 76.23, H: 3.89, N: 15.46, O: 4.41, % found C: 75.9, H: 4.2, N: 15.4).

Provenance & Evidence